Dr. Vladimir Baulin
- Vladimir Baulin is a Coordinator of EU funded Initial Training Network SNAL: Smart Nano-objects for Alteration of Lipid bilayers.
- Guest editor of the web themed issue “Interaction of nano-objects with lipid membranes” in Soft Matter journal.
- Develops Single Chain Mean Field (SCMF) theory, a simulation tool able to predict the properties of nanostructures given the microscopic details of its polymeric constituents. Recent application of the SCMF theory is the modelling of interaction of phospholipid bilayers with nano-objects and self-assembled structures.
- Designs nano-structured antibacterial surfaces inspired by insect wing surfaces.
- Works on a theoretical model for orientation of microtubules, constituents of cell cytoskeleton. This mechanism of microtubule orientation induced by mutual collisions between individual microtubules in 2D and 3D leads to global ordering and formation of orientation domains.
- Contributes to Poisson-Boltzmann theory of interpolyelectrolyte complexes with IPEC Solver.
- Lomonosov Moscow State University, Moscow, Russia: Master in physics (with Honours), 1994 – 2000
- Commissariat à l’Energie Atomique, Grenoble, France, PhD in physics, 2000 – 2003
Theory and simulation of soft matter: polymers, surfactants, colloids, liquid crystals.
Biophysics: self-organization of microtubules in living cells, modelling of interaction of phospholipid bilayers with nano-objects: carbon nanotubes, polymers, nanoparticles.
- “Race for the surface”: eukaryotic cells can win
ACS Appl. Mater. Interfaces: 8(34) 22025-22031 (2016)
Vy T. H. Pham, Vi Khanh Truong, Anna Orlowska, Shahram Ghanaati, Mike Barbeck, Patrick Booms, Alex James Fulcher, Chris M. Bhadra, Ricardas Buividas, Vladimir A Baulin, Charles James Kirkpatrick, Pauline Doran, David E. Mainwaring, Saulius Juodkazis, Russell J Crawford, and Elena P. Ivanova
With an aging population and the consequent increasing use of medical implants, …
- The Bioeffects Resulting from Prokaryotic Cells and Yeast Being Exposed to an 18 GHz Electromagnetic Field
PLoS ONE 11(7): e0158135 (2016)
The Hong Phong Nguyen , Vy T. H. Pham , Song Ha Nguyen , Vladimir A. Baulin, Rodney J. Croft, Brian Phillips, Russell J. Crawford, Elena P. Ivanova
The mechanisms by which various biological effects are triggered by exposure to an electromagnetic field are not fully understood and have been the subject of debate. Here, the effects …
- Peroxidised phospholipid bilayers: insight from Coarse-Grained Molecular Dynamics simulations
Soft Matter, 12, 263-271 (2016)
Yachong Guo, Vladimir Baulin and Fabrice Thalmann
An original coarse-grained model for peroxidised phospholipids is presented, based on the MARTINI lipid force field. This model results from a combination of thermodynamic modelling and structural information on the area per lipid, which have been made available recently. The resulting coarse-grained lipid molecules form stable bilayers, and a set of elastic …
- Self-organised nanoarchitecture of titanium surfaces influences the attachment of Staphylococcus aureus and Pseudomonas aeruginosa bacteria
Applied Microbiology and Biotechnology (2015) 99 (16), 6831-6840 DOI: 10.1007/s00253-015-6572-7
Vi K. Truong, Vy T. H. Pham, A. Medvedev, R. Lapovok, Y. Estrin, T. C. Lowe, V. Baulin, V. Boshkovikj, C. J. Fluke, R. J. Crawford, E. P. Ivanova
The surface nanotopography and architecture of medical implant devices are important factors that can control the extent of bacterial attachment. The ability to prevent bacterial attachment substantially reduces the possibility of …
- Efficient and Stable Method to Solve Poisson–Boltzmann Equation with Steep Gradients
Computational Electrostatics for Biological Applications
2015, pp 111-119 DOI: 10.1007/978-3-319-12211-3_5
Beibei Huang and Vladimir A. Baulin
This work describes a method to solve Poisson–Boltzmann Equation (PBE) with steep gradients when common methods of solving non-linear equations do not converge or work inefficiently. This is particularly the case for relatively large boundary conditions leading to rapid changes of the solution in a narrow interval. The method uses adaptive …
- Mechanism of dynamic reorientation of cortical microtubules due to mechanical stress
Biophysical Chemistry, (2015) 207, 82–89 DOI: 10.1016/j.bpc.2015.09.004
Alexander Muratov and Vladimir A. Baulin
Directional growth caused by gravitropism and corresponding bending of plant cells has been explored since 19th century, however, many aspects of mechanisms underlying the perception of gravity at the molecular level are still not well known. Perception of gravity in root and shoot gravitropisms is usually attributed to gravisensitive cells, called statocytes, which exploit …
- Graphene Induces Formation of Pores That Kill Spherical and Rod-Shaped Bacteria
ACS Nano, DOI: 10.1021/acsnano.5b03368 (2015)
Vy T. H. Pham, Vi Khanh Truong, Matthew D. J. Quinn, Shannon M. Notley, Yachong Guo, Vladimir A. Baulin, Mohammad Al Kobaisi, Russell J. Crawford, and Elena P. Ivanova
Pristine graphene, its derivatives, and composites have been widely reported to possess antibacterial properties. Most of the studies simulating the interaction between bacterial cell membranes and the surface of …
- General model of phospholipid bilayers in fluid phase within the single chain mean field theory
J. Chem. Phys. 140, 174903 (2014)
Yachong Guo, Sergey Pogodin and Vladimir A. Baulin
Coarse-grained model for saturated phospholipids: 1,2-didecanoyl-sn-glycero-3-phosphocholine (DCPC), 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and unsaturated phospholipids: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), 1,2- dioleoyl-sn-glycero-3-phosphocholine (DOPC) is introduced within the single chain mean field theory. A single set of parameters adjusted for DMPC bilayers gives an adequate description of equilibrium and mechanical properties …
- Nanotopography as a trigger for the microscale, autogenous and passive lysis of erythrocytes
J. Mater. Chem. B, 2 (19), 2785-2948 (2014)
Vy T. H. Pham, Vi Khanh Truong, David E. Mainwaring, Yachong Guo, Vladimir Baulin, Mohammad Al Kobaisi, Gediminas Gervinskas, Saulius Juodkazis, Wendy R. Zeng, Pauline Doran, Russell J Crawford and Elena P. Ivanova
Microscale devices are increasingly being developed for diagnostic analysis although conventional lysis as an initial step presents limitations due to scale or …
- Lipid oxidation induces structural changes in biomimetic membranes
Soft Matter, 10, 4241-4247 (2014)
G. Weber, T. Charitat, M. S. Baptista, A. F. Uchoa, C. Pavani, H. C. Junqueira, Y. Guo, V. A. Baulin, R. Itri, C. M. Marques, A. P. Schroder
Oxidation can intimately influence and structurally compromise the levels of biological self-assembly embodied by intracellular and plasma membranes. Lipid peroxidation, a natural metabolic outcome of life with oxygen under light, …