Dr. Vladimir Baulin

Education

    • Lomonosov Moscow State University, Moscow, Russia: Master in physics (with Honours), 1994 – 2000
    • Commissariat à l’Energie Atomique, Grenoble, France, PhD in physics, 2000 – 2003 

Research interests

Theory and simulation of soft matter: polymers, surfactants, colloids, liquid crystals.

Biophysics: self-organization of microtubules in living cells, modelling of interaction of phospholipid bilayers with nano-objects: carbon nanotubes, polymers, nanoparticles.

Recent Topics:

Active projects

Membrane-active block copolymers

Membrane-active nanoparticles

Membrane-active nanostructured surfaces

Membrane-active peptides

Recent publications

2016

  • Direct proof of spontaneous translocation of lipid-covered hydrophobic nanoparticles through a phospholipid bilayer

    Science Advances 2 (11), e1600261 (2016)
    Yachong Guo, Emmanuel Terazzi, Ralf Seemann, Jean Baptiste Fleury and Vladimir A. Baulin

    Hydrophobic nanoparticles introduced into living systems may lead to increased toxicity, can activate immune cells, or can be used as nanocarriers for drug or gene delivery. It is generally accepted that small hydrophobic nanoparticles are blocked by lipid bilayers and accumulate in the bilayer core, whereas big nanoparticles …

  • Adsorption of Human Plasma Albumin and Fibronectin onto Nanostructured Black Silicon Surfaces

    Langmuir: 10.1021/acs.langmuir.6b02601 (2016)
    Duy H. K. Nguyen, Vy T. H. Pham, Mohammad Al Kobaisi, Chris M. Bhadra, Anna Orlowska, Shahram Ghanaati, Berardo Mario Manzi, Vladimir A Baulin, Saulius Juodkazis, Peter Kingshott, Russell J Crawford, and Elena P. Ivanova

    The protein adsorption of two human plasma proteins, albumin (Alb) and fibronectin (Fn) onto synthetic nanostructured bactericidal material, black silicon (bSi) surfaces (that contain an …

  • “Race for the surface”: eukaryotic cells can win

    ACS Appl. Mater. Interfaces: 8(34) 22025-22031 (2016)
    Vy T. H. Pham, Vi Khanh Truong, Anna Orlowska, Shahram Ghanaati, Mike Barbeck, Patrick Booms, Alex James Fulcher, Chris M. Bhadra, Ricardas Buividas, Vladimir A Baulin, Charles James Kirkpatrick, Pauline Doran, David E. Mainwaring, Saulius Juodkazis, Russell J Crawford, and Elena P. Ivanova

    With an aging population and the consequent increasing use of medical implants, …

  • The Bioeffects Resulting from Prokaryotic Cells and Yeast Being Exposed to an 18 GHz Electromagnetic Field

    PLoS ONE 11(7): e0158135 (2016)
    The Hong Phong Nguyen , Vy T. H. Pham , Song Ha Nguyen , Vladimir A. Baulin, Rodney J. Croft, Brian Phillips, Russell J. Crawford, Elena P. Ivanova

    The mechanisms by which various biological effects are triggered by exposure to an electromagnetic field are not fully understood and have been the subject of debate. Here, the effects …

  • Peroxidised phospholipid bilayers: insight from Coarse-Grained Molecular Dynamics simulations

    Soft Matter, 12, 263-271 (2016)
    Yachong Guo, Vladimir Baulin and Fabrice Thalmann

    An original coarse-grained model for peroxidised phospholipids is presented, based on the MARTINI lipid force field. This model results from a combination of thermodynamic modelling and structural information on the area per lipid, which have been made available recently. The resulting coarse-grained lipid molecules form stable bilayers, and a set of elastic …

2015

  • Self-organised nanoarchitecture of titanium surfaces influences the attachment of Staphylococcus aureus and Pseudomonas aeruginosa bacteria

    Applied Microbiology and Biotechnology (2015) 99 (16), 6831-6840 DOI: 10.1007/s00253-015-6572-7
    Vi K. Truong, Vy T. H. Pham, A. Medvedev, R. Lapovok, Y. Estrin, T. C. Lowe, V. Baulin, V. Boshkovikj, C. J. Fluke, R. J. Crawford, E. P. Ivanova

    The surface nanotopography and architecture of medical implant devices are important factors that can control the extent of bacterial attachment. The ability to prevent bacterial attachment substantially reduces the possibility of …

  • Efficient and Stable Method to Solve Poisson–Boltzmann Equation with Steep Gradients

    Computational Electrostatics for Biological Applications
    2015, pp 111-119 DOI: 10.1007/978-3-319-12211-3_5
    Beibei Huang and Vladimir A. Baulin

    This work describes a method to solve Poisson–Boltzmann Equation (PBE) with steep gradients when common methods of solving non-linear equations do not converge or work inefficiently. This is particularly the case for relatively large boundary conditions leading to rapid changes of the solution in a narrow interval. The method uses adaptive …

  • Mechanism of dynamic reorientation of cortical microtubules due to mechanical stress

    Biophysical Chemistry, (2015) 207, 82–89 DOI: 10.1016/j.bpc.2015.09.004
    Alexander Muratov and Vladimir A. Baulin
    Directional growth caused by gravitropism and corresponding bending of plant cells has been explored since 19th century, however, many aspects of mechanisms underlying the perception of gravity at the molecular level are still not well known. Perception of gravity in root and shoot gravitropisms is usually attributed to gravisensitive cells, called statocytes, which exploit …

  • Graphene Induces Formation of Pores That Kill Spherical and Rod-Shaped Bacteria

    ACS Nano, DOI: 10.1021/acsnano.5b03368 (2015)
    Vy T. H. Pham, Vi Khanh Truong, Matthew D. J. Quinn, Shannon M. Notley, Yachong Guo, Vladimir A. Baulin, Mohammad Al Kobaisi, Russell J. Crawford, and Elena P. Ivanova

    Pristine graphene, its derivatives, and composites have been widely reported to possess antibacterial properties. Most of the studies simulating the interaction between bacterial cell membranes and the surface of …

2014

  • General model of phospholipid bilayers in fluid phase within the single chain mean field theory

    J. Chem. Phys. 140, 174903 (2014)
    Yachong Guo, Sergey Pogodin and Vladimir A. Baulin

    Coarse-grained model for saturated phospholipids: 1,2-didecanoyl-sn-glycero-3-phosphocholine (DCPC), 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and unsaturated phospholipids: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), 1,2- dioleoyl-sn-glycero-3-phosphocholine (DOPC) is introduced within the single chain mean field theory. A single set of parameters adjusted for DMPC bilayers gives an adequate description of equilibrium and mechanical properties …

  • Nanotopography as a trigger for the microscale, autogenous and passive lysis of erythrocytes

    J. Mater. Chem. B, 2 (19), 2785-2948 (2014)
    Vy T. H. Pham, Vi Khanh Truong, David E. Mainwaring, Yachong Guo, Vladimir Baulin, Mohammad Al Kobaisi,   Gediminas Gervinskas, Saulius Juodkazis, Wendy R. Zeng, Pauline Doran, Russell J Crawford and Elena P. Ivanova

    Microscale devices are increasingly being developed for diagnostic analysis although conventional lysis as an initial step presents limitations due to scale or …

  • Lipid oxidation induces structural changes in biomimetic membranes

    Soft Matter, 10, 4241-4247 (2014)
    G. Weber, T. Charitat, M. S. Baptista, A. F. Uchoa, C. Pavani, H. C. Junqueira, Y. Guo, V. A. Baulin, R. Itri, C. M. Marques, A. P. Schroder

    Oxidation can intimately influence and structurally compromise the levels of biological self-assembly embodied by intracellular and plasma membranes. Lipid peroxidation, a natural metabolic outcome of life with oxygen under light, …

Other years

soft matter group