Research

Kinetic evolution of DOPC lipid bilayers exposed to α-cyclodextrins

Soft Matter, , (2018)
Monika Kluzek, Marc Schmutz, Carlos M. Marques and Fabrice Thalmann
Cyclodextrins are cyclic oligosaccharides capable of forming inclusion complexes with a variety of molecules, and as such have been recognized as a pharmaceutical and biotechnological asset. Cyclodextrins are known to interact with the components of cell membranes, and this correlates with a significant […]

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Influence of a pH-sensitive polymer on the structure of monoolein cubosomes

Soft Matter, 13, 7571-7577 (2017)
Monika Kluzek, Arwen I. I. Tyler, Shiqi Wang, Rongjun Chen, Carlos M. Marques, Fabrice Thalmann, John M. Seddon, Marc Schmutz
Cubosomes consist in submicron size particles of lipid bicontinuous cubic phases stabilized by surfactant polymers. They provide an appealing road towards the practical use of lipid cubic phases for pharmaceutical and cosmetic […]

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Fundamentals and applications of lipid membrane biophysics

Horsley Park, 22nd-24th September 2015

Researchers from the ITN-SNAL network have met again to discuss the frontiers in the biophysics and biochemistry of lipid membranes. Throughout the two-day meeting (22.09.2015 – 24.09.2015) held in Horsley Park, UK, young researchers had a unique opportunity for active interactions with experts in the field. By showing their latest results […]

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Strasbourg: Principles of Imaging for Membrane systems

Dates: 30 November – 3 December 2015
Location: Institut Charles Sadron (23, Rue de Loess, 67034, Strasbourg, France)
Core training courses will cover such topics as methodology, models, and statistical estimation and hypothesis tests. Essential background and computational models for modelling lipid bilayers and their interactions with nano-objects will also be provided.

Given the large differences in background between experimental […]

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ESR8-S: Kinetics of nanoscale structural changes occurring in small unilamellar vesicles

Experimental investigation of unilamellar vesicles using microscopy techniques
Contact
Monika Kluzek
Description
Experimental project on small unilamellar lipid vesicles (SUV) interacting with nanoparticles, with special emphasis on the use of transmission electron microscopy (cryo-TEM). This project will consist in elaborating, characterizing and studying in detail decorated liposomes, using state of the art techniques such as EM tomography and time […]

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