Copenhagen, Denmark

Theoretical and experimental thermodynamics and spectroscopy of biological systems. Transitions in biomembranes, artificial lipid membranes and proteins. This includes studies on melting transitions, shape changes of lipid vesicles, protein unfolding, relaxation, and permeability.

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Selection of relevant publications





Gallaher, Jill, Katarzyna Wodzi?ska, Thomas Heimburg, and Martin Bier. 2010. "Ion-channel-like behavior in lipid bilayer membranes at the melting transition." Physical Review E, 81 (6).

Gudmand, Martin, Susana Rocha, Nikos Hatzakis, Kalina Peneva, Klaus Müllen, Dimitrios Stamou, Hiroshi Uji-I, Johan Hofkens, Thomas Bjørnholm, and Thomas Heimburg. 2010. "Influence of Lipid Heterogeneity and Phase Behavior on Phospholipase A2 Action at the Single Molecule Level." Biophysical Journal, 98 (9): 1873-1882.

Heimburg, T.. 2010. "Lipid ion channels." Biophysical Chemistry, 150 (1-3): 2-22.

Blicher, Andreas, Katarzyna Wodzinska, Matthias Fidorra, Mathias Winterhalter, and Thomas Heimburg. 2009. "The Temperature Dependence of Lipid Membrane Permeability, its Quantized Nature, and the Influence of Anesthetics." Biophysical Journal, 96 (11): 4581-4591.

Fidorra, M., Thomas Heimburg, and H.M. Seeger. 2009. "Melting of individual lipid components in binary lipid mixtures studied by FTIR spectroscopy, DSC and Monte Carlo simulations." Biochimica et Biophysica Acta (BBA) - Biomembranes, 1788 (3): 600-607.

Fidorra, Matthias, Thomas Heimburg, and Luis Bagatolli. 2009. "Direct Visualization of the Lateral Structure of Porcine Brain Cerebrosides/POPC Mixtures in Presence and Absence of Cholesterol." Biophysical Journal, 97 (1): 142-154.

Gudmand, M., Matthias Fidorra, T. Bjørnholm, and T. Heimburg. 2009. "Diffusion and Partitioning of Fluorescent Lipid Probes in Phospholipid Monolayers." Biophysical Journal, 96 (11): 4598-4609.

Wunderlich, B., C. Leirer, A.-L. Idzko, U.F. Keyser, A. Wixforth, V.M. Myles, T. Heimburg, and M.F. Schneider. 2009. "Phase-State Dependent Current Fluctuations in Pure Lipid Membranes." Biophysical Journal, 96 (11): 4592-4597.

Oliynyk, Vitaliy, Markus Jäger, Thomas Heimburg, Vitaly Buckin, and Udo Kaatze. 2008. "Lipid membrane domain formation and alamethicin aggregation studied by calorimetry, sound velocity measurements, and atomic force microscopy." Biophysical Chemistry, 134 (3): 168-177.

Heimburg, Thomas and Andrew Jackson. 2007. "The Thermodynamics of General Anesthesia." Biophysical Journal, 92 (9): 3159-3165.

Oliynyk, Vitaliy, Udo Kaatze, and Thomas Heimburg. 2007. "Defect formation of lytic peptides in lipid membranes and their influence on the thermodynamic properties of the pore environment." Biochimica et Biophysica Acta (BBA) - Biomembranes, 1768 (2): 236-245.


Hac, Agnieszka, Heiko Seeger, Matthias Fidorra, and Thomas Heimburg. 2005. "Diffusion in Two-Component Lipid Membranes—A Fluorescence Correlation Spectroscopy and Monte Carlo Simulation Study." Biophysical Journal, 88 (1): 317-333.