Mainz, Germany

Various aspects of investigative pathology, which aims at unraveling the mechanisms by which diseases arise and progress.

Related posts from this resource

All facilities are available in the REPAIR-lab of the institute for state-of-the-art cell and molecular biology, including tissue culture, biochemical analysis (ELISA, cell-EIA, Western blot), modern microscopic techniques including immunocytochemistry (confo-cal laser scanning microscopy as well as quantitative morphometric analysis of human cells in both static and dynamic culture), cell transfection by plasmid vectors, nucleic acid analysis for gene expression

Selection of relevant publications

Freese, Christian, Matthew Gibson, Harm-Anton Klok, Ronald Unger, and C. Kirkpatrick. 2012. "Size- and Coating-Dependent Uptake of Polymer-Coated Gold Nanoparticles in Primary Human Dermal Microvascular Endothelial Cells." Biomacromolecules, 13 (5): 1533-1543.

Freese, Christian, Chiara Uboldi, Matthew Gibson, Ronald Unger, Babette Weksler, Ignacio Romero, Pierre-Olivier Couraud, and C Kirkpatrick. 2012. "Uptake and cytotoxicity of citrate-coated gold nanospheres: Comparative studies on human endothelial and epithelial cells." Particle and Fibre Toxicology, 9 (1): 23.

Kasper, Jennifer, Maria Hermanns, Christoph Bantz, Olga Koshkina, Thomas Lang, Michael Maskos, Christine Pohl, Ronald Unger, and C. Kirkpatrick. 2012. "Interactions of silica nanoparticles with lung epithelial cells and the association to flotillins." Archives of Toxicology.

Kasper, Jennifer, Iris Hermanns, Michael Maskos, Christoph Bantz, and James Kirkpatrick. 2009. "The toxic effect of monodisperse amorphous silica particles studied on an in vitro model of the human air–blood barrier." Toxicology Letters, 189.