Research

Polymer micelles as drug carriers

Block copolymer micelles are composed of polymer chains with sequences of hydrophilic and hydrophobic blocks. In a dilute aqueous solution, they form spherical or cylindrical nano-objects comprised of several chains with a hydrophobic core and extended hydrophilic corona. Lipophilic drugs can be dissolved in the core of these micelles, while the corona will assure solubility […]

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Cyclodextrins and their applications

Cyclodextrins can complexate with polymers and thus can be grafted to surfaces. Grafted layers of sliding polymers are constructed from polymers threading through ring-like molecules grafted to a surface. Such grafting mode allows the polymer chains to freely slide inside the ring-like molecules, thus providing additional degree of freedom for grafted polymers.
A cyclic molecule of a cyclodextrin consist […]

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