Research

Self-assembly of interpolyelectrolyte complexes and their interaction with lipid membranes

 Electrostatic interactions are instrumental in determining the structure and function of living organisms, biopolymers and drug delivery systems. Charged macromolecules can self-assemble and aggregate into compact intermolecular complexes.
This ability of oppositely charged polymers to form finite size complexes determines their biological function, which for example is important in gene transfection and compactization of DNA, that provide promising alternatives to viral vectors. […]

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IPEC Solver: Numerical simulation tool to study inter-polyelectrolyte complexation

Comp. Phys. Comm., 184 (9), 2221–2229 (2013)
B. Huang and V.A. Baulin

IPEC Solver is a Windows program designed to analyze the stability of core–shell inter-polyelectrolyte complexes formed by complexation of oppositely charged block copolymers. The two-dimensional size distribution of the complexes composed by different numbers of positively or negatively charged polyelectrolytes is calculated based on the […]

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Self-assembly of spherical interpolyelectrolyte complexes from oppositely charged polymers

V. A. Baulin and E. Trizac
Soft Matter, 8 (25), 6755 – 6766 (2012)
The formation of inter-polyelectrolyte complexes from the association of oppositely charged polymers in an electrolyte is studied. The charged polymers are linear oppositely charged polyelectrolytes, with possibly a neutral block. This leads to complexes with a charged core, and a more dilute corona […]

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