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Influence of a pH-sensitive polymer on the structure of monoolein cubosomes
Soft Matter, 13, 7571-7577 (2017) Monika Kluzek, Arwen I. I. Tyler, Shiqi Wang, Rongjun Chen, Carlos M. Marques, Fabrice Thalmann, John M. Seddon, Marc Schmutz Cubosomes consist in submicron size part...
pH-Responsive, Lysine-Based, Hyperbranched Polymers Mimicking Endosomolytic Cell-Penetrating Peptides for Efficient Intracellular Delivery
Chem. Mater., DOI: 10.1021/acs.chemmater.7b00054 (2017). Shiqi Wang and Rongjun Chen The insufficient delivery of biomacromolecular therapeutic agents into the cytoplasm of mammalian cells remains a m...
Membrane-Anchoring, Comb-Like Pseudopeptides for Efficient, pH-Mediated Membrane Destabilization and Intracellular Delivery
ACS Appl. Mater. Interfaces, Article ASAP (2017) Siyuan Chen, Shiqi Wang, Michal Kopytynski, Marie Bachelet, and Rongjun Chen Endosomal release has been identified as a rate-limiting step for intracel...
Amino Acid Based Hydrogels with Dual Responsiveness for Oral Drug Delivery
Macromol. Biosci. (2016) Shiqi Wang, Xiaoxue Liu, Ignacio J. Villar-Garcia and Rongjun Chen This study reports a series of novel amino acid based dual-responsive hydrogels. Prepared by a facile one-p...
Workshop in Salou
The 4th workshop on biomaterials and their interactions with biological and model membranes was held in Salou (October 19th — 21th). Following up to the previous three workshops in 2011, 2013 a...
Summary of the Meeting in Cambridge 1 October 2014
1-2 October 2014 – Cambridge, Department of Chemical Engineering at the University of Cambridge. After months of discussions and proposals conducted by supervisors from each host institution an...
ESR5-L: Synthesis and characterization of functional biomimetic polymers for intracellular delivery
Chemical synthesis, characterisation of polymers and nano-objects Objectives This project is focused on development of functional biomimetic polymers which can traverse across cellular membranes to de...